SAPERAS, NÚRIA

Curriculum

Edifici ETSEIB, PG0 (23:34)
Av. Diagonal, 647
Campus Sud - UPC
08028 BARCELONA
Tel 93 401 66 87
Fax 93 401 09 78
nuria.saperasupc.edu

Personal information

Name:

Present position:

Department:

Center:

Nuria SAPERAS

Professor

Chemical Engineering

Universitat Politècnica de Catalunya

Research Interest

- Molecular biology, recombinant DNA technology.

- Protein-DNA interactions, chromatin remodelling (especially sperm chromatin remodelling).

- DNA remodelling associated proteins: structure and function.

- Molecular biology, recombinant DNA technology.
- Protein-DNA interactions, chromatin remodelling (especially sperm chromatin remodelling).
- DNA remodelling associated proteins: structure and function..

Selected Publications

E. Fonfría-Subirós, F. Acosta-Reyes, N. Saperas, J. Pous, J.A. Subirana and J.L. Campos Crystal structure of a complex of DNA with one AT-hook of HMGA1. PLoS One", 7: e37120(1-5) (2012)

M Chiva, N. Saperas and E. Ribes Complex chromatin condensation patterns and nuclear protein transitions during spermiogenesis. Tissue Cell, 43:367-376 (2011)

J.M. Eirín-López, L.J. Frehlick, M. Chiva, N. Saperas and J. Ausió The sperm proteins from amphioxus mirror its basal position among chordates and redefine the origin of vertebrate protamines. Mol. Biol. Evol., 25: 1705-1713 (2008)

N. Saperas, M. Chiva, M.T. Casas, J.L. Campos, J.M. Eirín-López, L.J. Frehlick, C. Prieto, J.A. Subirana and J. Ausió A unique vertebrate histone H1-related protamine-like protein results in an unusual sperm chromatin organization. FEBS J., 273: 4548-4561(2006)

C. Arnan, C. Prieto, M. Chiva, L. Salvany, J. Ausió, J.A. Subirana and N. Saperas Analysis of the stability and function of nucleoplasmin through cysteine mutants Archives Biochem. Biophys., 437: 205-214 (2005)

L. Salvany, M. Chiva, C. Arnan, J. Ausió, J.A. Subirana and N. Saperas Mutation of the small acidic tract A1 drastically reduces nucleoplasmin activity. FEBS Letters, 576: 353-357 (2004)

J.D. Lewis, N. Saperas, Y. Song, Mª José Zamora, M. Chiva and J. Ausió Histone H1 and the origin of protamines PNAS (P Natl Acad Sci USA), 101: 4148-4152 (2004)

C. Arnan, N. Saperas, C. Prieto, M. Chiva and J. Ausió Interaction of nucleoplasmin with core histones J. Biol. Chem., 278: 31319-31324 (2003)

C. Prieto, N. Saperas, C. Arnan, M.H. Hills, X. Wang, M. Chiva, R. Aligué, J.A. Subirana and J. Ausió Nucleoplasmin interaction with protamines. Involvement of the polyglutamic tract. Biochemistry, 41: 7802-7810 (2002)

N. Saperas, J. Ausió, D. Lloris and M. Chiva On the evolution of protamines in bony fish. Alternatives to the “retroviral horizontal transmission” hypothesis. J. Mol. Evol., 39: 282-295 (1994).